Cyclopeptide Alkaloids from Hymenocardia acida
نویسندگان
چکیده
منابع مشابه
New 14-Membered Cyclopeptide Alkaloids from Zizyphus oxyphylla Edgew
Two new 14-membered cyclopeptide alkaloids, Oxyphylline B (4) and Oxyphylline C (5), along with three known 13-membered cyclopeptide alkaloids, were isolated from stem and roots of Zizyphus oxyphylla Edgew. The compounds were tested for antibacterial activity. Oxyphylline B (4) showed comparatively better antibacterial activities against Escherichia coli (MIC, 5 μg/mL) than other compounds. Thi...
متن کاملAntifertility activity of aqueous ethanolic extract of Hymenocardia acida stem bark in female rats
BACKGROUND Hymenocardia acida is traditionally used in African herbal medicine and has numerous therapeutic benefits. But little is known about its potentially negative effects on pregnant women. OBJECTIVE The aim of the present study was to evaluate the antifertility effect of aqueous ethanolic extract of Hymenocardia acida stem bark in female Wistar rats. MATERIALS AND METHODS Four groups...
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The effect of methanolic extract of Hymenocardia acida leaves on diabetes and associated lipidemia were investigated on experimentally-induced diabetic rats. The extract did not demonstrate any acutely toxic effect in rats within the dose range (250 mg/kg - 2000 mg/kg) employed in the study; hence it was well tolerated by the rats. In all experiments, the anti-diabetic effects were dose-depende...
متن کاملAntiplasmodial Activity, Cytotoxicity and Structure-Activity Relationship Study of Cyclopeptide Alkaloids.
Cyclopeptide alkaloids are polyamidic, macrocyclic compounds, containing a 13-, 14-, or 15-membered ring. The ring system consists of a hydroxystyrylamine moiety, an amino acid, and a β-hydroxy amino acid; attached to the ring is a side chain, comprised of one or two more amino acid moieties. In vitro antiplasmodial activity was shown before for several compounds belonging to this class, and in...
متن کاملantifertility activity of aqueous ethanolic extract of hymenocardia acida stem bark in female rats
background: hymenocardia acida is traditionally used in african herbal medicine and has numerous therapeutic benefits. but little is known about its potentially negative effects on pregnant women. objective: the aim of the present study was to evaluate the antifertility effect of aqueous ethanolic extract of hymenocardia acida stem bark in female wistar rats. materials and methods: four groups ...
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ژورنال
عنوان ژورنال: Journal of Natural Products
سال: 2016
ISSN: 0163-3864,1520-6025
DOI: 10.1021/acs.jnatprod.6b00131